Health Claims

Taking NMN supplements for a few months might boost a key molecule in your blood that's involved in keeping your cells healthy as you age — but we don’t know yet if it actually slows aging.

Giving a supplement called nicotinamide riboside to rats on a high-fat diet might help them absorb more fat and energy, but it doesn’t seem to do anything if they’re eating regular food.

Taking a supplement called nicotinamide riboside for three months doesn’t seem to change the types or balance of gut bacteria in middle-aged, overweight men who don’t have diabetes.

Giving mice a supplement called nicotinamide riboside for three months changed the types of gut bacteria they had — some increased, others decreased — which might mean this supplement affects mouse gut health in a specific way.

Giving rats a special vitamin-like supplement called nicotinamide riboside for three months seems to boost certain 'good' gut bacteria, especially when they're eating a high-fat diet.

Giving rats a special vitamin-like supplement called nicotinamide riboside every day for 12 weeks seemed to help them gain less belly fat, even when eating fatty food.

Taking 250 mg of NMN every day for a few months doesn’t change body fat or muscle mass in healthy older guys, even though their muscles may work better.

Taking a daily 250 mg NMN supplement for a couple of months might help older men get stronger and move better — like gripping things tighter, walking faster, and standing up from a chair more easily — without changing their body fat or muscle mass.

Taking a 250 mg NMN supplement every day for a few weeks might boost a key molecule in your blood that helps your cells make energy and slows down some aging effects.

We don’t have any solid medical studies showing whether getting NAD+ through an IV or shot actually helps with aging or wellness — so we don’t know if it works or if it’s safe for that purpose.

We're not sure if boosting NAD+ actually helps people feel younger or healthier — studies have mixed or unclear results.

Taking NR or NMN by mouth seems to be safe for people over several weeks or months, with no serious side effects seen so far in studies.

Giving older mice supplements like NR or NMN might help their energy levels, reduce inflammation, and improve how well their bodies work—but the results aren't the same in every study.

Taking NR or NMN supplements by mouth seems to boost a key molecule called NAD+ in your blood, which scientists think might be good for aging, but we don’t know yet if it actually makes a real difference to health.

Even though taking NR or NMN boosts a molecule called NAD+ in the blood, we don’t actually have solid proof it makes people stronger, healthier, sharper, or more energetic.

After being given through an IV, NMN and NR end up in your gut through bile, where your gut bacteria turn them into a form of vitamin B3 that your body can use to make an important energy molecule called NAD+.

If you take antibiotics that wipe out your gut bacteria, your body can't turn a supplement called nicotinamide riboside into a form that helps make an important molecule called NAD+, so it doesn't work anymore.

If your body shows higher levels of a molecule called NAAD after taking NR or NMN supplements, it might mean your body is using a special pathway that only works with niacin (nicotinic acid) to make energy molecules.

When you take NR or NMN supplements, your gut bacteria turn them into a form of vitamin B3, which your body then uses to make an important molecule called NAD+ that helps keep your cells healthy.

Older people have more oxidative damage in their muscles, especially if they’re not active—but regular exercisers have less damage, similar to younger people.

An inflammation-related molecule called kynurenic acid builds up in older people’s muscles and is linked to weaker muscles and less efficient movement.

Older adults with more NAD+ in their muscles tend to have better-functioning mitochondria, which are the energy factories in cells.

Older adults who walk more steps each day tend to have higher levels of a key molecule in their muscles that's linked to youth and energy — especially if they hit over 13,000 steps, their levels look like those of young people. But if they take fewer than 7,500 steps, their levels are much lower.

Older people have lower levels of a key molecule in their muscles that helps keep cells healthy, especially if they're not active — but those who stay active, like endurance athletes, tend to keep their levels much higher.