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Taking creatine for a few weeks can give young, active guys a boost in short bursts of power, help them lift heavier weights, and let them do more reps — basically making their muscles work better...
If young, healthy guys take creatine with sugary drinks or a special mix of protein and sugar, less creatine comes out in their pee over 24 hours compared to taking it with just water.
If young, healthy guys take creatine with a sugary drink or a special mix of sugar and amino acids, their insulin levels spike faster than if they take creatine with just water.
If a young, healthy guy takes 5 grams of creatine with just water, his body absorbs it faster than if he takes it with carbs or with a mix of protein, amino acids, and carbs — and you can see that in...
If young, healthy guys take creatine with a mix of sugar, protein bits, and certain amino acids, it triggers about as much insulin as taking creatine with just a lot of sugar — and both help the body...
You don’t have to take carbs every time you take creatine, but doing so might help your muscles soak up more creatine if you're trying to build strength.
When you eat carbs, your body releases insulin, which helps shuttle creatine into your muscles more effectively—like a key that unlocks the door for creatine when sugar is around.
If you take creatine with carbs after working out, your body absorbs about 25% more of it because the carbs raise your insulin, which helps shuttle creatine into your muscles.
If young, healthy guys take a lot of creatine for 5 days straight, their muscles soak it up and end up with about 21% more creatine inside them.
Doing a tough leg workout with lots of sets makes your leg muscles start building new proteins much faster—2 to 3 times more than usual—right after the workout.
Taking a lot of creatine for 5 days doesn’t seem to boost muscle repair or growth right after a workout in young, healthy guys—even though it does increase creatine levels in their muscles. So,...
Cyclocreatine kills brain tumor cells in rats by making them swell up, but it stops ovarian cancer cells in humans in a totally different way we don’t yet understand.
In rat brain tumor cells, a substance called cyclocreatine gets pulled in using energy and sodium, but when sugar levels drop, this process slows down a lot—showing it needs energy from sugar to work...
When scientists gave a substance called cyclocreatine to two types of cancer cells, one kind (from rat brain tumors) stored a modified version of it, but the other kind (from human ovarian tumors)...
Cyclocreatine slows down the growth of certain cancer cells in a lab dish, but it doesn’t harm their outer layer or energy supply — so it probably works in a different way.
When guys who lift weights gain muscle, their muscle cells also hold more water — and this happens whether or not they take creatine. It suggests that growing muscle might be linked to how much water...
If you're a guy who lifts weights, taking creatine won't make you hold more water outside your cells compared to just training — the water increase seems to come from working out, not the supplement.
If you're a guy who lifts weights, taking creatine might help you gain more muscle and hold onto more water inside your cells than just training alone.
If you're a guy who lifts weights, taking creatine for 8 weeks can help you gain muscle and hold more water inside your muscle cells — but the water doesn't increase more than the muscle does, so...
Taking creatine every day for two weeks doesn’t change how much water is in or around your cells — even though the balance between them might shift a little — at least in young women who work out...
Taking a fake supplement (like sugar powder) for two weeks doesn’t change body water balance in young female athletes, so if real creatine does change it, the effect is likely from creatine itself.
Taking creatine for two weeks — whether a little or a lot — doesn’t change weight or body composition in young women who work out regularly.
Taking 5 grams of creatine every day for two weeks doesn’t seem to change how water is distributed in the body for young women who work out regularly.
Taking 20 grams of creatine every day for two weeks might help young active women hold more water inside their cells, which could support muscle function.